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Mocravimod hydrochloride

CAS No. 509088-69-1

Mocravimod hydrochloride( KRP-203 )

Catalog No. M26300 CAS No. 509088-69-1

Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mocravimod hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).
  • Description
    Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1). (In Vivo):In mHC-disparate rat heart allografts, Mocravimod hydrochloride(orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection. Mocravimod hydrochloride ameliorates atherosclerosis in LDL-R(-/-) Mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Inbred male DA (MHC haplotype: RT1a) rats Dosage:0.1 and 1 mg/kg Administration:Orally; daily; for 100 days.Result:Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.
  • Synonyms
    KRP-203
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    gluconeogenesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    509088-69-1
  • Formula Weight
    480.44
  • Molecular Formula
    C24H27Cl2NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 200 mg/mL (416.28 mM)
  • SMILES
    Cl.NC(CO)(CO)CCc1ccc(Sc2cccc(OCc3ccccc3)c2)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Murray AF, et, al. Phenylpropanoid Glycerol Glucosides Attenuate Glucose Production in Hepatocytes. ACS Omega. 2019 Jun 19;4(6):10670-10676.
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